SCHEMBL29530970

SCHEMBL29530970

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nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ DPP7 Q9UHL4 1/20 0.42
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ CTSC P53634 4/20 0.39
▸ CALCRL Q16602 1/20 0.39
▸ REN P00797 1/20 0.36
▸ KEAP1 Q14145 1/20 0.36
▸ PRCP P42785 1/20 0.36
▸ CYP1A2 P05177 1/20 0.35
▸ CYP3A4 P08684 1/20 0.35
▸ CYP2D6 P10635 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29475359 0.95 DPP7 (0.39) DPP7MEN1KMT2ACTSCCALCRL
SCHEMBL30112831 0.91 DPP7 (0.41) DPP7MEN1KMT2ACTSCCALCRL
SCHEMBL29641658 0.91 CALCRL (0.45) DPP7MEN1KMT2ACTSCCALCRL
SCHEMBL29367741 0.89 DPP7 (0.43) DPP7MEN1KMT2ACTSCREN
SCHEMBL30572916 0.88 REN (0.43) DPP7MEN1KMT2ARENKEAP1
SCHEMBL31031592 0.88 NMT1 (0.40) CALCRL
SCHEMBL30511778 0.87 DPP7 (0.42) DPP7MEN1KMT2ACTSCCALCRL
SCHEMBL30193415 0.87 DPP7 (0.44) DPP7MEN1KMT2ACTSCCALCRL
SCHEMBL31688177 0.86 PDCD1LG2 (0.45) DPP7MEN1KMT2ACTSCCALCRL
SCHEMBL38657878 0.86 CALCRL (0.43) DPP7MEN1KMT2ACTSCCALCRL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12312390-B2 Rapid-acting insulin analogues of enhanced stability CASE WESTERN RESERVE UNIVERSITY (US) 2025-05-27 — — US disclosed
US-20220112262-A1 RAPID-ACTING INSULIN ANALOGUES OF ENHANCED STABILITY CASE WESTERN RESERVE UNIVERSITY 2022-04-14 — — US disclosed
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