⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439058 | 1.00 | — | — | |
| SCHEMBL3890553 | 1.00 | — | — | |
| SCHEMBL28279170 | 0.98 | — | — | |
| SCHEMBL30102424 | 0.98 | — | — | |
| SCHEMBL10433683 | 0.83 | INMT (0.37) | — | |
| SCHEMBL6509714 | 0.72 | INMT (0.61) | — | |
| SCHEMBL12437181 | 0.69 | — | — | |
| SCHEMBL3656314 | 0.69 | — | — | |
| SCHEMBL10969327 | 0.69 | — | — | |
| SCHEMBL3606378 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111548347-B | Pyrazole compound containing 2-cyanoimino-1, 3-thiazolidine heterocycle and preparation method and application thereof | 南通大学 | 2022-11-04 | — | — | CN | claimed |
| US-11390594-B2 | Procedure for the preparation of 2-cyanoimino-1,3-thiazolidine | BAYER CROPSCIENCE LP (US) | 2022-07-19 | — | — | US | claimed |
| CN-114394939-A | Synthesis method of cimetidine | 河北科技大学 | 2022-04-26 | — | — | CN | claimed |
| CN-107674070-B | Cyanoimine thiazolidine furan carboxamide compound and preparation method and application thereof | 华南农业大学 | 2020-12-29 | — | — | CN | claimed |
| US-20200347024-A1 | PROCEDURE FOR THE PREPARATION OF 2-CYANOIMINO-1,3-THIAZOLIDINE | BAYER CROPSCIENCE LP | 2020-11-05 | — | — | US | claimed |
| US-10752600-B2 | Procedure for the preparation of 2-cyanoimino-1,3-thiazolidine | BAYER CROPSCIENCE LP (US) | 2020-08-25 | — | — | US | claimed |
| CN-111548347-A | Pyrazole compound containing 2-cyanoimino-1, 3-thiazolidine heterocycle and preparation method and application thereof | 南通大学 | 2020-08-18 | — | — | CN | claimed |
| CN-109354590-B | Synthesis method of thiacloprid | 山东省联合农药工业有限公司 | 2020-06-23 | — | — | CN | claimed |
| US-20190152933-A1 | Procedure for the Preparation of 2-Cyanoimino-1,3-Thiazolidine | BAYER CROPSCIENCE LP | 2019-05-23 | — | — | US | claimed |
| EP-3350172-A1 | PROCEDURE FOR THE PREPARATION OF 2-CYANOIMINO-1,3-THIAZOLIDINE | Bayer Cropscience LP (US) | 2018-07-25 | — | — | EP | claimed |
| EP-1466910-B1 | PROCESS FOR PRODUCING 2-CYANOIMINO-1,3-THIAZOLIDINE | NIPPON CARBIDE KOGYO KK (JP) | 2008-03-19 | — | — | EP | claimed |
| US-6858737-B2 | Process for producing 2-cyanoimino-1,3-thiazolidine | NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) | 2005-02-22 | — | — | US | claimed |
| US-20040235918-A1 | Process for producing 2-cyanoimino-1,3-thiazolidine | NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) | 2004-11-25 | — | — | US | claimed |
| EP-1466910-A1 | PROCESS FOR PRODUCING 2-CYANOIMINO-1,3-THIAZOLIDINE | Nippon Carbide Kogyo Kabushiki Kaisha (JP) | 2004-10-13 | — | — | EP | claimed |
| EP-1460068-A1 | PROCESS FOR PRODUCING 2-CYANOIMINO-1,3-THIAZOLIDINE | Nippon Carbide Kogyo Kabushiki Kaisha (JP) | 2004-09-22 | — | — | EP | claimed |
| US-6750351-B2 | REACTING SODIUM CYANIDE, SODIUM HYDROXIDE, METHANOL, LOWER ALCOHOL, CHLORINE AND CYANAMIDE TO FORM A CARBONIMIDIC ACID ESTER INTERMEDIATE, CYCLIZATION WITH 2-AMINO MERCAPTOETHANE; HIGH QUALITY CRYSTAL, GOOD YIELD AND HIGH PURITY | NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) | 2004-06-15 | — | — | US | claimed |
| US-20030130327-A1 | Reacting an alkali cyanide compound, an alkali hydroxide, a lower alcohol and chlorine in an aqueous solution, then adding a cyanamide, extracting, and washing with a reducing agent | NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) | 2003-07-10 | — | — | US | claimed |
| EP-0695744-B1 | Process for the preparation of cyanimino-1,3-thiazolidine | BAYER AG (DE) | 1997-10-08 | — | — | EP | claimed |
| US-5574165-A | Process for the preparation of cyanoimino-1,3-thiazolidines | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-12 | — | — | US | claimed |
| EP-0695744-A1 | Process for the preparation of cyanimino-1,3-thiazolidine | BAYER AG (DE) | 1996-02-07 | — | — | EP | claimed |