Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.48 |
| ▸ | BCR | P11274 | 3/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | ABL2 | P42684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20188754 | 1.00 | ABL1 (0.48) | ABL1BCRPDGFRBPDGFRAHDAC1 | |
| SCHEMBL20188007 | 0.87 | AURKA (0.45) | AURKA | |
| SCHEMBL21799119 | 0.80 | — | — | |
| SCHEMBL20188270 | 0.79 | — | — | |
| SCHEMBL30114704 | 0.79 | — | — | |
| SCHEMBL21799086 | 0.78 | AURKA (0.49) | AURKA | |
| SCHEMBL20188707 | 0.76 | AURKA (0.47) | AURKA | |
| SCHEMBL20188200 | 0.75 | AURKA (0.53) | AURKA | |
| SCHEMBL30114845 | 0.75 | AURKA (0.53) | AURKA | |
| SCHEMBL20188260 | 0.75 | AURKA (0.58) | ABL1BCRPDGFRBPDGFRAAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3544685-B1 | HETROARYLAMINE COMPOUNDS FOR MODULATING THE HEDGEHOG PATHWAY AND PREPARING METHOD AND USES THEREOF | DEV CT BIOTECHNOLOGY (TW) | 2023-01-04 | — | — | EP | claimed |
| CN-110139692-B | Heteroaryl amine compounds for modulating hedgehog pathway and methods of making and using the same | 财团法人生物技术开发中心 | 2023-08-25 | — | — | CN | disclosed |
| EP-3544685-B1 | HETROARYLAMINE COMPOUNDS FOR MODULATING THE HEDGEHOG PATHWAY AND PREPARING METHOD AND USES THEREOF | DEV CT BIOTECHNOLOGY (TW) | 2023-01-04 | — | — | EP | disclosed |