Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187744 | 1.00 | BCHE (0.46) | BCHEAURKAHTR2CMCHR1CSNK1D | |
| SCHEMBL20188166 | 0.92 | AURKA (0.44) | AURKAABL1 | |
| SCHEMBL30530307 | 0.92 | AURKA (0.44) | AURKAABL1 | |
| SCHEMBL30530317 | 0.91 | BCHE (0.45) | BCHEHTR2CMCHR1CSNK1DCSNK1E | |
| SCHEMBL20188373 | 0.91 | BCHE (0.45) | BCHEHTR2CMCHR1CSNK1DCSNK1E | |
| SCHEMBL30114852 | 0.88 | BCHE (0.44) | BCHEAURKAHTR2CMCHR1 | |
| SCHEMBL20187754 | 0.88 | BCHE (0.44) | BCHEAURKAHTR2CMCHR1 | |
| SCHEMBL20190260 | 0.86 | AURKA (0.48) | AURKAABL1BCR | |
| SCHEMBL21799066 | 0.85 | ABL1 (0.54) | HTR2CMCHR1ABL1BCR | |
| SCHEMBL30530294 | 0.85 | ABL1 (0.54) | HTR2CMCHR1ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139692-B | Heteroaryl amine compounds for modulating hedgehog pathway and methods of making and using the same | 财团法人生物技术开发中心 | 2023-08-25 | — | — | CN | disclosed |
| EP-3544685-B1 | HETROARYLAMINE COMPOUNDS FOR MODULATING THE HEDGEHOG PATHWAY AND PREPARING METHOD AND USES THEREOF | DEV CT BIOTECHNOLOGY (TW) | 2023-01-04 | — | — | EP | disclosed |