Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 3/20 | 0.39 |
| ▸ | CCR2 | P41597 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17543490 | 1.00 | ALDH1A1 (0.59) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL14485349 | 0.82 | ALDH1A1 (0.62) | ALDH1A1KMT2ASMN1; SMN2MAPTGAA | |
| SCHEMBL25715170 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL17531636 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL17543687 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KMT2ASMN1; SMN2KDM4EHTT | |
| SCHEMBL5622578 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL13419298 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL29931936 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KMT2ASMN1; SMN2KDM4EHTT | |
| SCHEMBL21590283 | 0.79 | MAPT (0.48) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL17543128 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KMT2AHPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884044-B | Piperidine derivatives | 大塚制药株式会社 | 2023-01-31 | — | — | CN | disclosed |