Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | REN | P00797 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PEPD | P12955 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29380028 | 0.97 | ACE (0.46) | ACERENKDM4EF2LMNA | |
| SCHEMBL29576017 | 0.94 | CAPN1 (0.42) | ACERENKDM4EF2LMNA | |
| SCHEMBL30159321 | 0.93 | CAPN1 (0.43) | ACERENKDM4EF2LMNA | |
| SCHEMBL30817465 | 0.90 | ACE (0.52) | ACERENKDM4EF2LMNA | |
| SCHEMBL30452849 | 0.90 | ACE (0.43) | ACERENKDM4EF2LMNA | |
| SCHEMBL30395175 | 0.89 | REN (0.39) | ACERENKDM4EF2LMNA | |
| SCHEMBL29765170 | 0.88 | CAPN1 (0.47) | ACERENKDM4EF2LMNA | |
| SCHEMBL29765258 | 0.88 | CAPN1 (0.47) | ACERENKDM4EF2LMNA | |
| SCHEMBL29765105 | 0.88 | CAPN1 (0.47) | ACERENKDM4EF2LMNA | |
| SCHEMBL29765176 | 0.88 | CAPN1 (0.47) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697375-A | Pharmaceutical composition comprising GLP-2 derivatives or long-acting conjugates thereof for the prevention or treatment of mucositis induced by radiotherapy, chemotherapy or a combination thereof | 韩美药品株式会社 | 2023-02-03 | — | — | CN | disclosed |