Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | FGB | P02675 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | PLEC | Q15149 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23226659 | 1.00 | STING1 (0.74) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL23226643 | 0.94 | STING1 (0.76) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL23226640 | 0.91 | STING1 (0.75) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL23226665 | 0.90 | STING1 (0.82) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL30116613 | 0.90 | STING1 (0.82) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL23226600 | 0.89 | STING1 (0.91) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL23226410 | 0.88 | STING1 (0.82) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL23226406 | 0.88 | STING1 (0.75) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL30116610 | 0.88 | STING1 (0.75) | STING1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL23226687 | 0.87 | STING1 (0.81) | STING1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409223-B | Amide compound and medical application thereof as STING inhibitor | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |