SCHEMBL30116751

SCHEMBL30116751

C1=C(c2cccnc2)CC(c2cccnc2)NC1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 12/20 0.53
CHRNA4 P43681 12/20 0.53
CHRNA7 P36544 7/20 0.53
CYP2A6 P11509 3/20 0.53
MEN1 O00255 2/20 0.45
CYP2D6 P10635 2/20 0.45
CYP2C19 P33261 2/20 0.45
KMT2A Q03164 2/20 0.45
CYP1A2 P05177 2/20 0.45
POLB P06746 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CYP2C9 P11712 1/20 0.45
CHRNA3 P32297 4/20 0.42
CHRNB4 P30926 3/20 0.42
CHRNB3 Q05901 2/20 0.42
CHRNA6 Q15825 2/20 0.42
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24154370 1.00 CHRNB2 (0.53) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
SCHEMBL30116728 1.00 CHRNB2 (0.53) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
SCHEMBL24155135 1.00 CHRNB2 (0.53) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
Hydrochloric Acid SCHEMBL30116747 0.98 CHRNB2 (0.51) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
Hydrochloric Acid SCHEMBL28973685 0.98 CHRNB2 (0.51) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
SCHEMBL24155127 0.93 CHRNB2 (0.51) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
SCHEMBL24154702 0.93 CHRNB2 (0.51) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
SCHEMBL30116726 0.93 CHRNB2 (0.51) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
Hydrochloric Acid SCHEMBL28973690 0.91 CHRNB2 (0.50) CHRNB2CHRNA4CHRNA7CYP2A6MEN1
Hydrochloric Acid SCHEMBL30116761 0.91 CHRNB2 (0.50) CHRNB2CHRNA4CHRNA7CYP2A6MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115698002-A Compositions and methods for parasite control 菲利普莫里斯生产公司 2023-02-03 CN disclosed