Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.37 |
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | RORC | P51449 | 9/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23926377 | 1.00 | KDM4E (0.38) | KDM4EMAPTTGFBR1THRBRORC | |
| SCHEMBL23926341 | 0.97 | RORC (0.38) | KDM4EMAPTTGFBR1THRBRORC | |
| SCHEMBL30118929 | 0.97 | RORC (0.38) | KDM4EMAPTTGFBR1THRBRORC | |
| SCHEMBL30118934 | 0.85 | RORC (0.37) | KDM4EMAPTTGFBR1THRBRORC | |
| SCHEMBL23926372 | 0.85 | RORC (0.37) | KDM4EMAPTTGFBR1THRBRORC | |
| SCHEMBL23926379 | 0.85 | KDM4E (0.39) | KDM4EMAPTTGFBR1THRBMAPK14 | |
| SCHEMBL30118895 | 0.85 | KDM4E (0.39) | KDM4EMAPTTGFBR1THRBMAPK14 | |
| SCHEMBL23926374 | 0.82 | RORC (0.36) | KDM4EMAPTTGFBR1THRBRORC | |
| SCHEMBL30118901 | 0.82 | RORC (0.36) | KDM4EMAPTTGFBR1THRBRORC | |
| SCHEMBL23926373 | 0.82 | GRM2 (0.46) | TGFBR1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168408-A1 | COMPOUNDS FOR AND METHODS OF TREATING DISEASES | Alterity Therapeutics Limited (AU) | 2023-04-26 | — | — | EP | disclosed |
| CN-115667256-A | Compounds for treating diseases and methods of treating diseases | 艾特里提治疗有限公司 | 2023-01-31 | — | — | CN | disclosed |