Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 6/20 | 0.32 |
| ▸ | JAK3 | P52333 | 5/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.32 |
| ▸ | ABL1 | P00519 | 5/20 | 0.32 |
| ▸ | EGFR | P00533 | 5/20 | 0.32 |
| ▸ | HCK | P08631 | 5/20 | 0.32 |
| ▸ | SRC | P12931 | 5/20 | 0.32 |
| ▸ | KDR | P35968 | 5/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.32 |
| ▸ | MTOR | P42345 | 5/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 5/20 | 0.32 |
| ▸ | PRKDC | P78527 | 5/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 2/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26983725 | 0.81 | JMJD6 (0.30) | RPS6KB1AKT1 | |
| SCHEMBL29156455 | 0.76 | JMJD6 (0.33) | RPS6KB1AKT1 | |
| SCHEMBL26983719 | 0.75 | PIM1 (0.33) | — | |
| SCHEMBL30050566 | 0.75 | PIM1 (0.33) | — | |
| SCHEMBL24783784 | 0.75 | JAK2 (0.41) | JAK2JAK1 | |
| SCHEMBL26983726 | 0.74 | SYK (0.37) | JAK2 | |
| SCHEMBL30780310 | 0.74 | SYK (0.37) | JAK2 | |
| SCHEMBL30780398 | 0.73 | — | — | |
| SCHEMBL30780446 | 0.72 | TYK2 (0.45) | JAK2JAK3JAK1 | |
| SCHEMBL26983737 | 0.72 | TYK2 (0.45) | JAK2JAK3JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551559-A1 | HETEROARYL COMPOUNDS AS INHIBITORS OF TYK2/JAK1, COMPOSITION AND APPLICATION THEREOF | Accro Bioscience (HK) Limited (HK) | 2025-05-14 | — | — | EP | disclosed |
| EP-4351562-A1 | HETEROARYL COMPOUNDS AS INHIBITORS OF TYK2, COMPOSITION AND APPLICATION THEREOF | Accro Bioscience (HK) Limited (HK) | 2024-04-17 | — | — | EP | disclosed |
| WO-2024010963-A1 | HETEROARYL COMPOUNDS AS INHIBITORS OF TYK2/JAK1, COMPOSITION AND APPLICATION THEREOF | ACCRO BIOSCIENCE (HK) LIMITED (CN) | 2024-01-11 | — | — | WO | disclosed |
| WO-2022261524-A1 | HETEROARYL COMPOUNDS AS INHIBITORS OF TYK2, COMPOSITION AND APPLICATION THEREOF | ACCRO BIOSCIENCE (HK) LIMITED (CN) | 2022-12-15 | — | — | WO | disclosed |