Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24753435 | 1.00 | ALDH1A1 (0.52) | ALDH1A1ESR2PDGFRBPDGFRAMEN1 | |
| SCHEMBL1664655 | 0.92 | ALDH1A1 (0.52) | ALDH1A1ESR2PDGFRBPDGFRAMEN1 | |
| SCHEMBL1441691 | 0.85 | ESR2 (0.49) | ALDH1A1ESR2PDGFRBPDGFRAMEN1 | |
| SCHEMBL629503 | 0.79 | ALDH1A1 (0.55) | ALDH1A1PDGFRBPDGFRAMEN1KMT2A | |
| SCHEMBL30775025 | 0.79 | ALDH1A1 (0.55) | ALDH1A1PDGFRBPDGFRAMEN1KMT2A | |
| SCHEMBL621353 | 0.76 | ALDH1A1 (0.52) | ALDH1A1PDGFRBPDGFRAMEN1KMT2A | |
| SCHEMBL361089 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2AKDM4EHTT | |
| SCHEMBL9912661 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ACASP1KDM4E | |
| SCHEMBL12928106 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HPGDNPC1 | |
| SCHEMBL2629408 | 0.76 | ALDH1A1 (0.46) | ALDH1A1ESR2PDGFRBPDGFRAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096858-A1 | COMPOUNDS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| EP-4351583-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 Therapeutics, Inc. (US) | 2024-04-17 | — | — | EP | disclosed |
| WO-2022261250-A1 | THERAPEUTICS FOR THE DEGRADATION OF MUTANT BRAF | C4 THERAPEUTICS, INC. (US) | 2022-12-15 | — | — | WO | disclosed |