Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 13/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23803880 | 1.00 | GPR52 (0.53) | GPR52THRBMRGPRX4NPC1LMNA | |
| SCHEMBL23803891 | 0.91 | GPR52 (0.54) | GPR52THRBNPC1LMNARAB9A | |
| SCHEMBL30120873 | 0.91 | GPR52 (0.54) | GPR52THRBNPC1LMNARAB9A | |
| SCHEMBL30120895 | 0.89 | GPR52 (0.52) | GPR52THRBNPC1LMNARAB9A | |
| SCHEMBL23803856 | 0.89 | GPR52 (0.52) | GPR52THRBNPC1LMNARAB9A | |
| SCHEMBL30152177 | 0.89 | GPR52 (0.52) | GPR52THRBNPC1LMNARAB9A | |
| SCHEMBL23803852 | 0.87 | GPR52 (0.56) | GPR52 | |
| SCHEMBL30120829 | 0.87 | GPR52 (0.56) | GPR52 | |
| SCHEMBL23803883 | 0.83 | GPR52 (0.55) | GPR52 | |
| SCHEMBL30120942 | 0.83 | GPR52 (0.55) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515681-B | GPR52 modulator compounds | 奈克斯拉制药英国有限公司 | 2024-09-03 | — | — | CN | disclosed |
| EP-4117784-A1 | GPR52 MODULATOR COMPOUNDS | Heptares Therapeutics Limited (GB) | 2023-01-18 | — | — | EP | disclosed |
| CN-115515681-A | GPR52 modulator compounds | 赫普泰雅治疗有限公司 | 2022-12-23 | — | — | CN | disclosed |