Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 18/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23803789 | 1.00 | GPR52 (0.55) | GPR52ALDH1A1TACR1 | |
| SCHEMBL23803849 | 0.90 | GPR52 (0.57) | GPR52 | |
| SCHEMBL30120969 | 0.90 | GPR52 (0.57) | GPR52 | |
| SCHEMBL30152179 | 0.89 | GPR52 (0.56) | GPR52 | |
| SCHEMBL23803837 | 0.89 | GPR52 (0.56) | GPR52 | |
| SCHEMBL23803890 | 0.88 | GPR52 (0.56) | GPR52 | |
| SCHEMBL30120850 | 0.88 | GPR52 (0.56) | GPR52 | |
| SCHEMBL23803883 | 0.87 | GPR52 (0.55) | GPR52 | |
| SCHEMBL30120942 | 0.87 | GPR52 (0.55) | GPR52 | |
| SCHEMBL23803891 | 0.86 | GPR52 (0.54) | GPR52ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4117784-B1 | GPR52 MODULATOR COMPOUNDS | NXERA PHARMA UK LTD (GB) | 2024-08-28 | — | — | EP | claimed |
| EP-4117784-A1 | GPR52 MODULATOR COMPOUNDS | Heptares Therapeutics Limited (GB) | 2023-01-18 | — | — | EP | claimed |
| EP-4117784-B1 | GPR52 MODULATOR COMPOUNDS | NXERA PHARMA UK LTD (GB) | 2024-08-28 | — | — | EP | disclosed |
| EP-4117784-A1 | GPR52 MODULATOR COMPOUNDS | Heptares Therapeutics Limited (GB) | 2023-01-18 | — | — | EP | disclosed |