Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CHKA | P35790 | 1/20 | 0.45 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.45 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24651118 | 1.00 | MGLL (0.49) | MGLLNR1H2PTGDR2SCN9AMEN1 | |
| SCHEMBL23349093 | 0.85 | MGLL (0.47) | MGLLPTGDR2MEN1KMT2AABHD6 | |
| SCHEMBL24651115 | 0.84 | MGLL (0.49) | MGLLNR1H2PTGDR2SCN9AMEN1 | |
| SCHEMBL23349094 | 0.83 | MGLL (0.56) | MGLLPTGDR2ABHD6PLA2G7CYP2D6 | |
| SCHEMBL13800153 | 0.81 | PTGDR2 (0.72) | MGLLPTGDR2SCN9AMEN1KMT2A | |
| SCHEMBL24650637 | 0.79 | NR1H2 (0.57) | NR1H2CHKARAD52BRAFKIT | |
| SCHEMBL20214464 | 0.79 | NR1H2 (0.61) | NR1H2MEN1KMT2ABRAFKIT | |
| SCHEMBL754058 | 0.78 | SMN1; SMN2 (0.54) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL1264281 | 0.77 | NR1H2 (0.62) | MGLLNR1H2SCN9AMEN1KMT2A | |
| SCHEMBL24650655 | 0.76 | PPARG (0.51) | MGLLCHKAKDM4EALDH1A1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212326-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-06 | — | — | WO | disclosed |