SCHEMBL30121071

SCHEMBL30121071

N=C(N)NCCC[C@@H]1NC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC1=O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 7/20 0.50
ITGAV P06756 3/20 0.50
ITGB5 P18084 1/20 0.50
ITGB1 P05556 1/20 0.49
ITGA5 P08648 1/20 0.49
MC4R P32245 8/20 0.48
MC5R P33032 8/20 0.48
MC3R P41968 8/20 0.48
MC1R Q01726 8/20 0.48
CXCR4 P61073 1/20 0.48
ITGA2B P08514 4/20 0.48
TSLP Q969D9 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30121037 1.00 ITGB3 (0.50) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL30121057 1.00 ITGB3 (0.50) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL24975089 0.94 ITGB3 (0.54) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL31668453 0.93 CXCR4 (0.58) CXCR4
SCHEMBL31668480 0.93 CXCR4 (0.58) CXCR4
SCHEMBL8207851 0.91 MC4R (0.48) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL27423920 0.91 MC4R (0.48) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL22872704 0.91 ITGB3 (0.59) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL20888358 0.91 ITGB3 (0.58) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL21766911 0.91 ITGB3 (0.58) ITGB3ITGAVITGB5ITGB1ITGA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243244-A1 CYCLIC CELL PENETRATING PEPTIDES ENTRADA THERAPEUTICS, INC. 2025-07-31 US disclosed
EP-4314016-A1 CYCLIC CELL PENETRATING PEPTIDES Entrada Therapeutics, Inc. (US) 2024-02-07 EP disclosed
WO-2022213118-A1 CYCLIC CELL PENETRATING PEPTIDES ENTRADA THERAPEUTICS, INC. (US) 2022-10-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243244-A1 CYCLIC CELL PENETRATING PEPTIDES SLC47A1, SLC47A2, VIP ITGB3 3430/4885ITGAV 2250/4885ITGB5 3685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.