Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23803647 | 1.00 | LMNA (0.53) | LMNAHPGDEGFRNPC1RAB9A | |
| SCHEMBL30031983 | 1.00 | LMNA (0.53) | LMNAHPGDEGFRNPC1RAB9A | |
| SCHEMBL30032553 | 0.90 | MCL1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL23803632 | 0.90 | MCL1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL30032667 | 0.90 | MCL1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL30031861 | 0.85 | GAA (0.56) | LMNAHPGDEGFRNPC1RAB9A | |
| SCHEMBL30032531 | 0.85 | GAA (0.56) | LMNAHPGDEGFRNPC1RAB9A | |
| SCHEMBL23803651 | 0.85 | GAA (0.56) | LMNAHPGDEGFRNPC1RAB9A | |
| SCHEMBL710202 | 0.82 | MAOB (0.63) | LMNAHPGDEGFRNPC1RAB9A | |
| SCHEMBL29717105 | 0.82 | MAOB (0.63) | LMNAHPGDEGFRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4118069-A1 | 2,5- OR 2,6-DISUBSTITUTED HYDROQUINONE DERIVATIVES WITH AT LEAST ONE CARBOXY, SULFO OR AMIDO GROUP USEFUL AS MEDICAMENTS | OM Pharma SA (CH) | 2023-01-18 | — | — | EP | disclosed |