Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.40 |
| ▸ | CASP3 | P42574 | 3/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24745514 | 1.00 | MTNR1A (0.41) | MTNR1AMTNR1BALDH1A1HTTGRM1 | |
| SCHEMBL24745431 | 0.90 | MTNR1A (0.41) | MTNR1AMTNR1BALDH1A1HTTCASP3 | |
| SCHEMBL24744929 | 0.84 | KDM4E (0.52) | MTNR1AMTNR1BALDH1A1NPC1MAPT | |
| SCHEMBL29098575 | 0.83 | KDM4E (0.44) | MTNR1AMTNR1BALDH1A1HTTGRM1 | |
| SCHEMBL24745633 | 0.81 | GRM1 (0.48) | ALDH1A1HTTGRM1CASP3PRNP | |
| SCHEMBL30122010 | 0.81 | GRM1 (0.48) | ALDH1A1HTTGRM1CASP3PRNP | |
| SCHEMBL24746866 | 0.81 | MAPT (0.40) | ALDH1A1HTTGRM1MAPT | |
| SCHEMBL2254145 | 0.76 | MTNR1A (0.48) | MTNR1AMTNR1BALDH1A1NPC1MAPT | |
| SCHEMBL24745619 | 0.76 | KDM4E (0.47) | MTNR1AMTNR1BALDH1A1RXFP1NPC1 | |
| SCHEMBL8354251 | 0.76 | GRM1 (0.50) | ALDH1A1HTTGRM1CASP3RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630414-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | Captor Therapeutics S.A. (PL) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121256-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2024-06-13 | — | — | WO | disclosed |
| EP-4347579-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | Captor Therapeutics S.A. (PL) | 2024-04-10 | — | — | EP | disclosed |
| WO-2022253713-A1 | TARGETED PROTEIN DEGRADATION USING BIFUNCTIONAL COMPOUNDS THAT BIND UBIQUITIN LIGASE AND TARGET MCL-1 PROTEIN | CAPTOR THERAPEUTICS S.A. (PL) | 2022-12-08 | — | — | WO | disclosed |