Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 2/20 | 0.41 |
| ▸ | FLT4 | P35916 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20446318 | 1.00 | ERN1 (0.46) | ERN1SRD5A2MAPTALDH1A1KMT2A | |
| SCHEMBL30122183 | 0.81 | AKR1C3 (0.43) | ERN1SRD5A2MAPTALDH1A1KMT2A | |
| SCHEMBL20446377 | 0.81 | AKR1C3 (0.43) | ERN1SRD5A2MAPTALDH1A1KMT2A | |
| SCHEMBL20447479 | 0.81 | NPC1 (0.48) | ERN1MAPTALDH1A1KMT2ATP53 | |
| SCHEMBL29872272 | 0.81 | NPC1 (0.48) | ERN1MAPTALDH1A1KMT2ATP53 | |
| SCHEMBL8479014 | 0.79 | CASP3 (0.51) | ERN1MAPTALDH1A1KMT2ATP53 | |
| SCHEMBL12332975 | 0.78 | TDP1 (0.51) | SRD5A2MAPTALDH1A1KMT2ANR4A1 | |
| SCHEMBL3025807 | 0.78 | KMT2A (0.61) | SRD5A2MAPTALDH1A1KMT2ANR4A1 | |
| SCHEMBL1822194 | 0.78 | NR4A1 (0.62) | SRD5A2MAPTALDH1A1NR4A1SLC10A6 | |
| SCHEMBL1247945 | 0.78 | NR4A1 (0.62) | SRD5A2MAPTALDH1A1NR4A1SLC10A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572252-B | Isoindolinone inhibitors of MDM2-P53 interaction with anticancer activity | 阿斯泰克斯治疗有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-115572252-A | Isoindolinone inhibitors of MDM2-P53 interaction with anti-cancer activity | 阿斯泰克斯治疗有限公司 | 2023-01-06 | — | — | CN | disclosed |