Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | PKM | P14618 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | CASP6 | P55212 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30918539 | 0.80 | MAPT (0.55) | MAPTKDM4ETDP1PKMHTT | |
| SCHEMBL30122661 | 0.77 | MEN1 (0.55) | MAPTKDM4ETDP1PKMHTT | |
| SCHEMBL4436189 | 0.77 | MEN1 (0.55) | MAPTKDM4ETDP1PKMHTT | |
| SCHEMBL28553829 | 0.77 | NQO2 (0.51) | MAPTKDM4ETDP1PKMHTT | |
| SCHEMBL27964543 | 0.77 | POLB (0.45) | MAPTKDM4ETDP1PKMHTT | |
| SCHEMBL30437811 | 0.73 | MAPT (0.52) | MAPTKDM4ETDP1PKMHTT | |
| SCHEMBL27190188 | 0.73 | MAPT (0.72) | MAPTKDM4ETDP1PKMHTT | |
| SCHEMBL24363301 | 0.72 | PARP1 (0.49) | MAPTHTTALDH1A1MEN1KMT2A | |
| SCHEMBL6865287 | 0.70 | MEN1 (0.48) | MAPTKDM4ETDP1PKMHTT | |
| SCHEMBL22049618 | 0.69 | MAPT (0.52) | MAPTKDM4EHTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253152-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2022-12-08 | — | — | WO | disclosed |