Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | CASP6 | P55212 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30918539 | 0.80 | MAPT (0.55) | POLBALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL30122661 | 0.77 | MEN1 (0.55) | POLBALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL28553829 | 0.77 | NQO2 (0.51) | POLBALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL4436189 | 0.77 | MEN1 (0.55) | POLBALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL30122630 | 0.77 | MAPT (0.48) | POLBALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL29612589 | 0.76 | MEN1 (0.44) | ALDH1A1MAPK1MAPTKDM4ETDP1 | |
| SCHEMBL20480525 | 0.76 | MEN1 (0.44) | ALDH1A1MAPK1MAPTKDM4ETDP1 | |
| SCHEMBL8856476 | 0.75 | POLB (0.50) | POLBALDH1A1MAPTKDM4ETDP1 | |
| SCHEMBL22803990 | 0.74 | BACE1 (0.45) | MAPTKDM4EHTTMEN1KMT2A | |
| SCHEMBL30626599 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPK1MAPTKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104177293-A | Synthesis method of 5-amino-7-trifluoromethyl quinoline and 5-trifluoromethyl-7-amino quinoline | SUZHOU KANGRUN PHARMACEUTICALS INC | 2014-12-03 | — | — | CN | disclosed |