Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 9/20 | 1.00 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.65 |
| ▸ | GRM5 | P41594 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15734191 | 1.00 | PDE10A (1.00) | PDE10ATGFBR1MAPK14GRM5NPC1 | |
| SCHEMBL15043339 | 0.87 | PDE10A (0.78) | PDE10ATGFBR1MAPK14GRM5NPC1 | |
| SCHEMBL30123690 | 0.87 | PDE10A (0.77) | PDE10ATGFBR1MAPK14GRM5NPC1 | |
| SCHEMBL30123641 | 0.87 | PDE10A (0.78) | PDE10ATGFBR1MAPK14GRM5NPC1 | |
| SCHEMBL15733668 | 0.87 | PDE10A (0.77) | PDE10ATGFBR1MAPK14GRM5NPC1 | |
| SCHEMBL15734407 | 0.83 | PDE10A (1.00) | PDE10ATGFBR1MAPK14GRM5NPC1 | |
| SCHEMBL15733281 | 0.83 | PDE10A (1.00) | PDE10ATGFBR1MAPK14GRM5NPC1 | |
| SCHEMBL15022257 | 0.83 | PDE10A (0.71) | PDE10ATGFBR1MAPK14 | |
| SCHEMBL15735701 | 0.82 | PDE10A (1.00) | PDE10ATGFBR1MAPK14GRM5NPC1 | |
| SCHEMBL15734464 | 0.82 | PDE10A (0.77) | PDE10ATGFBR1MAPK14GRM5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115484938-A | Composition and use thereof | 博善人工智能剑桥有限公司 | 2022-12-16 | — | — | CN | disclosed |