Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.78 |
| ▸ | GRM5 | P41594 | 3/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.53 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.53 |
| ▸ | BRAF | P15056 | 5/20 | 0.49 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15043339 | 1.00 | PDE10A (0.78) | PDE10AGRM5MAPK14MAPK13CSNK1D | |
| SCHEMBL30123690 | 0.89 | PDE10A (0.77) | PDE10AGRM5MAPK14MAPK13CSNK1D | |
| SCHEMBL15733668 | 0.89 | PDE10A (0.77) | PDE10AGRM5MAPK14MAPK13CSNK1D | |
| SCHEMBL15735701 | 0.88 | PDE10A (1.00) | PDE10AGRM5MAPK14BRAFKDM4E | |
| SCHEMBL15734464 | 0.88 | PDE10A (0.77) | PDE10AGRM5MAPK14MAPK13CSNK1D | |
| SCHEMBL30122884 | 0.88 | PDE10A (1.00) | PDE10AGRM5MAPK14BRAFKDM4E | |
| SCHEMBL15734407 | 0.88 | PDE10A (1.00) | PDE10AGRM5MAPK14KDM4EMEN1 | |
| SCHEMBL30122927 | 0.87 | PDE10A (1.00) | PDE10AGRM5MAPK14KDM4EMEN1 | |
| SCHEMBL15734191 | 0.87 | PDE10A (1.00) | PDE10AGRM5MAPK14KDM4EMEN1 | |
| SCHEMBL15022282 | 0.86 | PDE10A (0.59) | PDE10AMAPK14MAPK13CSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115484938-A | Composition and use thereof | 博善人工智能剑桥有限公司 | 2022-12-16 | — | — | CN | disclosed |