SCHEMBL30122975

SCHEMBL30122975

NCCCC[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 3/20 0.65
NTSR2 O95665 6/20 0.59
NTSR1 P30989 6/20 0.59
SORT1 Q99523 4/20 0.59
OPRD1 P41143 1/20 0.54
SLC6A2 P23975 1/20 0.54
F2 P00734 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30353452 0.97 OPRM1 (0.62) OPRM1NTSR2NTSR1SORT1SLC6A2
SCHEMBL30273400 0.94 OPRM1 (0.64) OPRM1NTSR2NTSR1SORT1OPRD1
SCHEMBL30497929 0.90 OPRM1 (0.64) OPRM1OPRD1SLC6A2F2
Lysine SCHEMBL185235 0.89 OPRM1 (0.66) OPRM1NTSR2NTSR1SORT1OPRD1
SCHEMBL31114383 0.88 OPRM1 (0.68) OPRM1NTSR2NTSR1SORT1OPRD1
SCHEMBL31679387 0.88 OPRM1 (0.66) OPRM1OPRD1SLC6A2F2
SCHEMBL31114332 0.87 OPRM1 (0.70) OPRM1NTSR2NTSR1SORT1OPRD1
SCHEMBL31114390 0.87 OPRM1 (0.64) OPRM1NTSR2NTSR1SORT1OPRD1
SCHEMBL31114540 0.87 OPRM1 (0.64) OPRM1NTSR2NTSR1SORT1OPRD1
SCHEMBL31114066 0.87 OPRM1 (0.64) OPRM1NTSR2NTSR1SORT1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370150-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS Intervet International B.V. (NL) 2024-05-22 EP disclosed
WO-2023285489-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS INTERVET INTERNATIONAL B.V. (NL) 2023-01-19 WO disclosed