Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.61 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.53 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | BRAF | P15056 | 10/20 | 0.51 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15733468 | 1.00 | PDE10A (0.61) | PDE10ACSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL15043350 | 0.86 | PDE10A (0.61) | PDE10ACSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL15735061 | 0.84 | PDE10A (0.64) | PDE10ACSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL30123648 | 0.84 | PDE10A (0.64) | PDE10ACSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL15733493 | 0.80 | PDE10A (0.68) | PDE10ACSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL15043339 | 0.80 | PDE10A (0.78) | PDE10ACSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL15733023 | 0.80 | PDE10A (0.61) | PDE10ACSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL30123641 | 0.80 | PDE10A (0.78) | PDE10ACSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL15745979 | 0.79 | PDE10A (0.66) | PDE10ACSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL15733219 | 0.79 | CSNK1D (0.65) | PDE10ACSNK1DCSNK1EMAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115484938-A | Composition and use thereof | 博善人工智能剑桥有限公司 | 2022-12-16 | — | — | CN | disclosed |