Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18644044 | 1.00 | IDO1 (0.37) | IDO1ABL1PNMTTAAR1AHR | |
| SCHEMBL30488129 | 0.79 | CYP4F2 (0.43) | IDO1ABL1PNMTTAAR1AHR | |
| SCHEMBL3745838 | 0.79 | IDO1 (0.38) | IDO1ABL1PNMTTAAR1AHR | |
| SCHEMBL507167 | 0.79 | CYP4F2 (0.43) | IDO1ABL1PNMTTAAR1AHR | |
| SCHEMBL9663794 | 0.78 | IDO1 (0.58) | IDO1PNMTTAAR1AHRTSHR | |
| SCHEMBL11947198 | 0.77 | IDO1 (0.37) | IDO1ABL1PNMTTAAR1AHR | |
| SCHEMBL1363230 | 0.77 | CSNK2A1 (0.46) | IDO1PNMTTAAR1CSNK2A1 | |
| SCHEMBL29086995 | 0.77 | IDO1 (0.64) | IDO1ABL1PNMTTAAR1AHR | |
| SCHEMBL12188730 | 0.77 | ABL1 (0.43) | IDO1ABL1PNMTTAAR1KMT2A | |
| SCHEMBL263603 | 0.77 | NOTUM (0.44) | IDO1ABL1PNMTTAAR1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113149971-B | 8- (indoletriazole) substituted coumarin compound and preparation method and application thereof | 港科鹏禾生物(苏州)有限公司 | 2022-12-16 | — | — | CN | disclosed |