SCHEMBL30488129

SCHEMBL30488129

Clc1ccc(CBr)cc1Br

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.43
CYP4A11 Q02928 1/20 0.43
IDO1 P14902 3/20 0.38
ABL1 P00519 1/20 0.37
PNMT P11086 2/20 0.35
TAAR1 Q96RJ0 1/20 0.35
TSHR P16473 2/20 0.35
TRPA1 O75762 1/20 0.35
ALDH1A1 P00352 1/20 0.35
AHR P35869 2/20 0.34
NOTUM Q6P988 1/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CSNK2A1 P68400 1/20 0.32
CYP3A4 P08684 1/20 0.32
CCR2 P41597 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL507167 1.00 CYP4F2 (0.43) CYP4F2CYP4A11IDO1ABL1PNMT
SCHEMBL20570318 0.82 PNMT (0.42) IDO1ABL1PNMTTAAR1ALDH1A1
SCHEMBL3745838 0.81 IDO1 (0.38) IDO1ABL1PNMTTAAR1TSHR
SCHEMBL507688 0.81 CYP4F2 (0.40) CYP4F2CYP4A11IDO1PNMTTAAR1
SCHEMBL10128 0.80 IDO1 (0.58) CYP4F2CYP4A11IDO1PNMTTAAR1
SCHEMBL29413271 0.80 IDO1 (0.58) CYP4F2CYP4A11IDO1PNMTTAAR1
SCHEMBL1363230 0.79 CSNK2A1 (0.46) IDO1PNMTTAAR1CSNK2A1
SCHEMBL11947198 0.79 IDO1 (0.37) IDO1ABL1PNMTTAAR1TSHR
SCHEMBL263603 0.79 NOTUM (0.44) IDO1ABL1PNMTTAAR1TSHR
SCHEMBL18644044 0.79 IDO1 (0.37) IDO1ABL1PNMTTAAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023107630-A2 AMINO ALCOHOL COMPOUNDS AND USES THEREOF Kineta, Inc. (US) 2023-06-15 WO disclosed