Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.59 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15733793 | 1.00 | GRM5 (0.59) | GRM5PDE10ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15022079 | 0.83 | PDE10A (0.51) | PDE10APDE4BPDE3BPDE3A | |
| SCHEMBL15735320 | 0.82 | GRM5 (0.51) | GRM5PDE10ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15745980 | 0.80 | BRAF (0.47) | PDE10APDE4BPDE3BPDE3A | |
| SCHEMBL30123641 | 0.78 | PDE10A (0.78) | GRM5PDE10ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15043339 | 0.78 | PDE10A (0.78) | GRM5PDE10ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15733106 | 0.75 | PDE10A (0.71) | GRM5PDE10ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15735281 | 0.72 | PDE10A (1.00) | GRM5PDE10ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4724002 | 0.70 | BRAF (0.53) | PDE10APDE4BPDE3BPDE3A | |
| SCHEMBL8119242 | 0.69 | PRMT5 (0.48) | PDE10ANPC1RAB9AKMT2APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115484938-A | Composition and use thereof | 博善人工智能剑桥有限公司 | 2022-12-16 | — | — | CN | disclosed |