SCHEMBL30123523

SCHEMBL30123523

C[C@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 13/20 0.54
NPY1R P25929 8/20 0.54
NPY5R Q15761 7/20 0.54
NPY2R P49146 4/20 0.54
BACE1 P56817 2/20 0.49
OPRM1 P35372 2/20 0.45
OPRD1 P41143 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30866922 0.95 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2RBACE1
SCHEMBL29531412 0.94 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31670476 0.93 BACE1 (0.53) NPY4RNPY1RNPY5RNPY2RBACE1
SCHEMBL29666731 0.91 BACE1 (0.57) NPY4RNPY1RNPY5RNPY2RBACE1
Opiorphin (2-5) SCHEMBL30549309 0.90 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30272524 0.90 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2R
SCHEMBL7645663 0.89 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL7645668 0.89 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL30632623 0.89 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29666714 0.89 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370150-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS Intervet International B.V. (NL) 2024-05-22 EP disclosed
WO-2023285489-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS INTERVET INTERNATIONAL B.V. (NL) 2023-01-19 WO disclosed