SCHEMBL7645663

SCHEMBL7645663

CC(NC(=O)C(Cc1ccccc1)NC(=O)C(N)CCCNC(=N)N)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 15/20 0.61
NPY1R P25929 9/20 0.61
NPY5R Q15761 8/20 0.61
NPY2R P49146 5/20 0.61
OPRM1 P35372 2/20 0.49
OPRD1 P41143 2/20 0.49
GNPAT O15228 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7645668 1.00 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL30866922 0.92 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL29531604 0.92 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL10940118 0.91 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL29666714 0.91 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL24059390 0.91 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2RGNPAT
SCHEMBL1727152 0.91 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2R
SCHEMBL1940080 0.91 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2R
SCHEMBL1727150 0.91 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2R
SCHEMBL4048021 0.90 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2RGNPAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001055713-A9 METHOD AND APPARATUS FOR SEPARATING POLYNUCLEOTIDES USING MONOLITHIC CAPILLARY COLUMNS TRANSGENOMIC INC (US) 2002-10-31 WO disclosed
EP-1235852-A2 METHOD AND APPARATUS FOR SEPARATING POLYNUCLEOTIDES USING MONOLITHIC CAPILLARY COLUMNS TRANSGENOMIC, Inc. (US) 2002-09-04 EP disclosed
WO-2001055713-A2 METHOD AND APPARATUS FOR SEPARATING POLYNUCLEOTIDES USING MONOLITHIC CAPILLARY COLUMNS TRANSGENOMIC, INC. (US) 2001-08-02 WO disclosed