Sugi Predict

Sugi Predict / Compounds / SCHEMBL30123606

SCHEMBL30123606

SCHEMBL30123606

NC(=O)CC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 3/20 0.52
▸ NPY2R P49146 3/20 0.52
▸ NPY4R P50391 3/20 0.52
▸ GHSR Q92847 2/20 0.52
▸ IL1RN P18510 1/20 0.52
▸ ERAP2 Q6P179 1/20 0.52
▸ OPRM1 P35372 1/20 0.51
▸ OPRD1 P41143 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30462941 0.95 NPY1R (0.52) NPY1RNPY2RNPY4RGHSRIL1RN
SCHEMBL31721034 0.93 GHSR (0.54) GHSRERAP2
SCHEMBL38662537 0.93 IL1RN (0.59) IL1RNERAP2
SCHEMBL7936370 0.93 ERAP1 (0.57) IL1RNERAP2OPRM1OPRD1
SCHEMBL7048050 0.93 ERAP1 (0.57) IL1RNERAP2OPRM1OPRD1
SCHEMBL7048052 0.93 ERAP1 (0.57) IL1RNERAP2OPRM1OPRD1
SCHEMBL29577523 0.92 ERAP1 (0.56) IL1RNERAP2OPRM1OPRD1
SCHEMBL29577107 0.92 ERAP1 (0.56) IL1RNERAP2OPRM1OPRD1
SCHEMBL30506405 0.91 GHSR (0.54) GHSRERAP2
SCHEMBL30254250 0.91 ACE (0.50) GHSRERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370150-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS Intervet International B.V. (NL) 2024-05-22 — — EP disclosed
WO-2023285489-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS INTERVET INTERNATIONAL B.V. (NL) 2023-01-19 — — WO disclosed
Send feedback