SCHEMBL30123623

SCHEMBL30123623

N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 5/20 0.54
▸ OPRD1 P41143 4/20 0.54
▸ ACE P12821 1/20 0.53
▸ SLC6A2 P23975 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29630550 0.96 OPRM1 (0.54) OPRM1OPRD1ACESLC6A2
SCHEMBL29630359 0.92 OPRM1 (0.53) OPRM1OPRD1ACESLC6A2
SCHEMBL29590543 0.90 OPRM1 (0.56) OPRM1OPRD1SLC6A2
SCHEMBL29666878 0.89 ACE (0.58) ACE
SCHEMBL29591216 0.89 SLC6A2 (0.63) OPRM1OPRD1SLC6A2
SCHEMBL31039947 0.88 SLC6A2 (0.62) OPRM1OPRD1ACESLC6A2
SCHEMBL30123533 0.88 SLC6A2 (0.62) OPRM1OPRD1ACESLC6A2
SCHEMBL29899126 0.88 ACE (0.55) OPRM1ACESLC6A2
SCHEMBL29630548 0.88 SLC6A2 (0.53) OPRM1OPRD1ACESLC6A2
SCHEMBL30800715 0.86 SLC6A2 (0.54) OPRM1ACESLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370150-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS Intervet International B.V. (NL) 2024-05-22 — — EP disclosed
WO-2023285489-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS INTERVET INTERNATIONAL B.V. (NL) 2023-01-19 — — WO disclosed
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