Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 3/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30124697 | 0.84 | JAK1 (0.46) | JAK1GPR119HDAC1CHRM2CHRM1 | |
| SCHEMBL25310135 | 0.82 | GPR119 (0.59) | JAK1GPR119HDAC1CHRM2CHRM1 | |
| SCHEMBL5041626 | 0.79 | HDAC1 (0.59) | JAK1GPR119HDAC1CHRM2CHRM1 | |
| SCHEMBL21262007 | 0.79 | HDAC1 (0.59) | JAK1GPR119HDAC1CHRM2CHRM1 | |
| SCHEMBL30250122 | 0.77 | JAK1 (0.45) | JAK1GPR119HDAC1CHRM2CHRM1 | |
| SCHEMBL25537463 | 0.77 | JAK1 (0.45) | JAK1GPR119HDAC1CHRM2CHRM1 | |
| SCHEMBL30930878 | 0.76 | JAK1 (0.41) | JAK1GPR119HDAC1CHRM2CHRM1 | |
| SCHEMBL30124006 | 0.76 | JAK1 (0.41) | JAK1GPR119HDAC1CHRM2CHRM1 | |
| SCHEMBL21405289 | 0.75 | JAK1 (0.47) | JAK1GPR119HDAC1CHRM2CHRM1 | |
| SCHEMBL29790234 | 0.75 | JAK1 (0.47) | JAK1GPR119HDAC1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4351560-A1 | ANTICANCER COMPOUNDS | The Regents of the University of California (US) | 2024-04-17 | — | — | EP | disclosed |
| CN-117794525-A | Anticancer compounds | 加利福尼亚大学董事会 | 2024-03-29 | — | — | CN | disclosed |
| WO-2022261204-A1 | ANTICANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-15 | — | — | WO | disclosed |