Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.33 |
| ▸ | BACE1 | P56817 | 4/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 2/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30124212 | 0.90 | CAPN1 (0.42) | CAPN1EPHB4GRM1GRM4PARP10 | |
| SCHEMBL24719482 | 0.90 | CAPN1 (0.42) | CAPN1EPHB4GRM1GRM4PARP10 | |
| SCHEMBL30124439 | 0.88 | CAPN1 (0.37) | CAPN1EPHB4GRM1GRM4ADORA2B | |
| SCHEMBL30124611 | 0.85 | CAPN1 (0.35) | CAPN1GRM1GRM4 | |
| SCHEMBL24720828 | 0.85 | CAPN1 (0.35) | CAPN1GRM1GRM4 | |
| SCHEMBL30124598 | 0.83 | EPHB4 (0.30) | EPHB4 | |
| SCHEMBL30124429 | 0.82 | CAPN1 (0.36) | CAPN1EPHB4ADORA2BPARP10PARP11 | |
| SCHEMBL30124385 | 0.82 | CAPN1 (0.37) | CAPN1EPHB4GRM1GRM4ADORA2B | |
| SCHEMBL24720270 | 0.82 | KARS1 (0.36) | EPHB4 | |
| SCHEMBL30124276 | 0.82 | KARS1 (0.36) | EPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4351560-A1 | ANTICANCER COMPOUNDS | The Regents of the University of California (US) | 2024-04-17 | — | — | EP | disclosed |
| CN-117794525-A | Anticancer compounds | 加利福尼亚大学董事会 | 2024-03-29 | — | — | CN | disclosed |
| WO-2022261204-A1 | ANTICANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-12-15 | — | — | WO | disclosed |