Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.54 |
| ▸ | ACP1 | P24666 | 2/20 | 0.53 |
| ▸ | GBA1 | P04062 | 2/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.48 |
| ▸ | PDE5A | O76074 | 4/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23723287 | 1.00 | SLC6A3 (0.54) | SLC6A3ACP1GBA1TLR9PDE5A | |
| SCHEMBL23747914 | 0.84 | SLC6A3 (0.54) | SLC6A3ACP1GBA1TLR9PDE5A | |
| SCHEMBL23747915 | 0.83 | CYP1A2 (0.57) | SLC6A3ACP1TLR9 | |
| SCHEMBL23747842 | 0.83 | GBA1 (0.55) | SLC6A3ACP1GBA1PDE5A | |
| SCHEMBL30125328 | 0.81 | TLR9 (0.63) | ACP1GBA1TLR9 | |
| SCHEMBL23723445 | 0.81 | TLR9 (0.63) | ACP1GBA1TLR9 | |
| SCHEMBL23747843 | 0.80 | SLC6A3 (0.49) | SLC6A3ACP1GBA1TLR9PDE5A | |
| SCHEMBL23747909 | 0.80 | PDE5A (0.54) | SLC6A3ACP1GBA1TLR9PDE5A | |
| SCHEMBL23723346 | 0.80 | PDE5A (0.48) | SLC6A3ACP1TLR9PDE5AHRH4 | |
| SCHEMBL30125141 | 0.80 | PDE5A (0.48) | SLC6A3ACP1TLR9PDE5AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100395-A1 | QUINAZOLINE COMPOUNDS AND THE USE THEREOF IN THE TREATMENT OF CANCER | Trobio Therapeutics Pty Ltd (AU) | 2022-12-14 | — | — | EP | disclosed |