Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.68 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.68 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.67 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23924205 | 1.00 | GABRA1 (0.68) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL4742531 | 0.91 | GABRA1 (0.58) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL7284420 | 0.82 | GABRA1 (0.78) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL30417619 | 0.82 | GABRA1 (0.78) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL7291769 | 0.81 | GABRA1 (1.00) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL11112915 | 0.81 | KDM4E (0.61) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL3249435 | 0.80 | MAPT (0.47) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL7381114 | 0.80 | GABRA1 (1.00) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL846416 | 0.80 | GABRA1 (0.74) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL22886423 | 0.80 | GABRA1 (0.74) | GABRA1GABRB2GABRB1GABRA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461056-A | Novel lymphoid specific tyrosine phosphatase (LYP) inhibitors | 普渡研究基金会 | 2022-12-09 | — | — | CN | disclosed |