Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30127058 | 0.88 | EGFR (0.49) | EGFRERBB2FGFR4 | |
| SCHEMBL30125765 | 0.86 | EGFR (0.51) | EGFRERBB2FGFR4 | |
| SCHEMBL30126357 | 0.86 | EGFR (0.51) | EGFRERBB2FGFR4 | |
| SCHEMBL30126489 | 0.86 | EGFR (0.48) | EGFRERBB2FGFR4 | |
| SCHEMBL30125755 | 0.86 | EGFR (0.48) | EGFRERBB2FGFR4 | |
| SCHEMBL30127470 | 0.85 | PIK3CD (0.46) | EGFR | |
| SCHEMBL30125773 | 0.81 | EGFR (0.69) | EGFRERBB2RAF1FLT1FGFR2 | |
| SCHEMBL30127467 | 0.79 | KDR (0.40) | EGFRERBB2FGFR4FLT1FGFR2 | |
| SCHEMBL30126998 | 0.76 | EGFR (0.49) | EGFRERBB2 | |
| SCHEMBL30127492 | 0.75 | EGFR (0.56) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266458-A1 | 6-HETEROCYCLOALKYL-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |