Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28707071 | 0.72 | CYP17A1 (0.43) | CYP17A1METAP1KCNQ4KCNQ5RXFP1 | |
| SCHEMBL10187654 | 0.72 | CYP17A1 (0.43) | CYP17A1METAP1KCNQ4KCNQ5LCK | |
| SCHEMBL18180255 | 0.71 | NPC1 (0.39) | CYP17A1METAP1LCKBRAFLMNA | |
| SCHEMBL24427976 | 0.71 | CYP17A1 (0.42) | CYP17A1METAP1KCNQ4KCNQ5RXFP1 | |
| SCHEMBL30739735 | 0.71 | CYP17A1 (0.44) | CYP17A1METAP1KCNQ4KCNQ5BRAF | |
| SCHEMBL7008829 | 0.71 | CYP17A1 (0.44) | CYP17A1PSMB8METAP1KCNQ4KCNQ5 | |
| SCHEMBL29021810 | 0.70 | CYP17A1 (0.44) | CYP17A1KCNQ4KCNQ5RXFP1LMNA | |
| SCHEMBL29069807 | 0.70 | CYP17A1 (0.41) | CYP17A1PSMB8METAP1KCNQ4KCNQ5 | |
| SCHEMBL31009176 | 0.70 | CYP17A1 (0.44) | CYP17A1KCNQ4KCNQ5RXFP1LMNA | |
| SCHEMBL29932426 | 0.70 | CYP17A1 (0.44) | CYP17A1KCNQ4KCNQ5RXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024249642-A1 | EGFR INHIBITORS | ACERAND THERAPEUTICS (HONG KONG) LIMITED (CN) | 2024-12-05 | — | — | WO | disclosed |
| WO-2022266458-A1 | 6-HETEROCYCLOALKYL-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |