Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30127990 | 1.00 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL16877915 | 1.00 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL16878459 | 0.94 | TSHR (0.31) | SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL2529301 | 0.91 | CYP2D6 (0.34) | SLC6A2SLC6A4SLC6A3TSHR | |
| Oxalic Acid SCHEMBL30335388 | 0.89 | SLC6A2 (0.30) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16878679 | 0.87 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL2538582 | 0.86 | — | — | |
| SCHEMBL19045056 | 0.86 | — | — | |
| SCHEMBL19045057 | 0.86 | — | — | |
| SCHEMBL503340 | 0.86 | ALDH1A1 (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3914600-B1 | THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2024-08-07 | — | — | EP | claimed |
| EP-3661941-B1 | THIAZOLOPYRIDINE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS | MERCK PATENT GMBH (DE) | 2022-12-14 | — | — | EP | claimed |