Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3012840 | 1.00 | HPGD (0.56) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL3112043 | 0.86 | HPGD (0.51) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL3867596 | 0.86 | POLB (0.49) | HPGDDPP4SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3866848 | 0.86 | POLB (0.49) | HPGDDPP4SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3876317 | 0.86 | POLB (0.49) | HPGDDPP4SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13036597 | 0.83 | HPGD (0.60) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL8479659 | 0.82 | HPGD (0.50) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL9456288 | 0.82 | HPGD (0.52) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL7436181 | 0.81 | HPGD (0.62) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL9456344 | 0.81 | HPGD (0.62) | HPGDTSHRPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2053040-A1 | Pregabalin intermediates and process for preparing them and Pregabalin | Chemo Ibérica, S.A. (ES) | 2009-04-29 | — | — | EP | claimed |
| CN-101848905-A | Process for the enantioselective preparation of pregabalin | ESTEVE LABOR DR | 2010-09-29 | — | — | CN | disclosed |
| US-20100197939-A1 | PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF PREGABALIN | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2010-08-05 | — | — | US | disclosed |
| US-20100197939-A1 | PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF PREGABALIN | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2010-08-05 | — | — | US | disclosed |
| US-20100197939-A1 | PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF PREGABALIN | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2010-08-05 | — | — | US | disclosed |
| EP-2178855-A1 | PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF PREGABALIN | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009053446-A2 | PREGABALIN INTERMEDIATES AND PROCESS FOR PREPARING THEM AND PREGABALIN | CHEMO IBÉRICA, S.A. (ES) | 2009-04-30 | — | — | WO | disclosed |
| EP-2053040-A1 | Pregabalin intermediates and process for preparing them and Pregabalin | Chemo Ibérica, S.A. (ES) | 2009-04-29 | — | — | EP | disclosed |
| WO-2009010554-A1 | PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF PREGABALIN | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2009-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197939-A1 | PROCESS FOR THE ENANTIOSELECTIVE PREPARATION OF PREGABALIN | GABRE, CYP2D6, GABRG2 | HPGD 536/4885TSHR 3410/4885PDE4A 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.