Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 18/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | BUB1 | O43683 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30708 | 0.86 | CCR4 (0.59) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL22446 | 0.83 | CCR4 (0.55) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL30728 | 0.78 | CCR4 (0.62) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL30085 | 0.78 | CCR4 (0.67) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL17876 | 0.78 | BUB1 (0.47) | CCR4P2RX7BUB1 | |
| SCHEMBL30582 | 0.77 | CCR4 (0.69) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL357460 | 0.76 | CCR4 (0.79) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL30525 | 0.75 | CCR4 (0.62) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL185247 | 0.74 | CCR4 (0.59) | CCR4CCR5FFAR4SLCO1B1 | |
| SCHEMBL186627 | 0.72 | CYP19A1 (0.43) | P2RX7BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025473-A1 | CC.CHEMOKINE RECEPTOR 4 ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2012-03-01 | — | — | WO | disclosed |