Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 13/20 | 0.59 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.55 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | GSK3B | P49841 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30129167 | 0.89 | EGFR (0.60) | EGFRFLT3MKNK1MKNK2HDAC1 | |
| SCHEMBL30219221 | 0.87 | MKNK1 (0.59) | EGFRFLT3MKNK1MKNK2HDAC1 | |
| SCHEMBL30108198 | 0.86 | MKNK1 (0.66) | EGFRFLT3MKNK1MKNK2HDAC1 | |
| SCHEMBL30129517 | 0.85 | EGFR (0.68) | EGFRFLT3MKNK1MKNK2HDAC1 | |
| SCHEMBL22695236 | 0.85 | EGFR (0.58) | EGFRFLT3MKNK1MKNK2HDAC1 | |
| SCHEMBL22695238 | 0.85 | EGFR (0.58) | EGFRFLT3MKNK1MKNK2HDAC1 | |
| SCHEMBL30748657 | 0.85 | EGFR (0.58) | EGFRFLT3MKNK1MKNK2HDAC1 | |
| SCHEMBL29423844 | 0.85 | EGFR (0.58) | EGFRFLT3MKNK1MKNK2HDAC1 | |
| SCHEMBL28400775 | 0.84 | EGFR (0.61) | EGFRFLT3MKNK1MKNK2HDAC1 | |
| SCHEMBL30108161 | 0.84 | EGFR (0.61) | EGFRFLT3MKNK1MKNK2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563310-B | 4- (1-methylindol-3-yl) pyrimidine derivative and application thereof | 浙江工业大学 | 2022-10-11 | — | — | CN | disclosed |