⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1303005 | 1.00 | — | — | |
| SCHEMBL29388226 | 0.88 | OR51E2 (0.33) | — | |
| SCHEMBL2565061 | 0.88 | OR51E2 (0.33) | — | |
| SCHEMBL23070931 | 0.86 | FKBP5 (0.35) | — | |
| SCHEMBL31712935 | 0.79 | — | — | |
| SCHEMBL30978396 | 0.77 | — | — | |
| SCHEMBL31712928 | 0.76 | — | — | |
| SCHEMBL1448583 | 0.73 | CHEK1 (0.37) | — | |
| SCHEMBL30100337 | 0.73 | CHEK1 (0.37) | — | |
| SCHEMBL3046656 | 0.72 | CDC7 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655695-B | Substituted furopyrimidine compounds as PDE1 inhibitors | 达特神经科学有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-111655695-B | Substituted furopyrimidine compounds as PDE1 inhibitors | 达特神经科学有限公司 | 2025-05-27 | — | — | CN | disclosed |
| EP-4146190-A2 | COMBINATION TREATMENT FOR FUMARATE-RELATED DISEASES | Imcyse SA (BE) | 2023-03-15 | — | — | EP | disclosed |
| CN-115531366-A | Method of treating multiple sclerosis | 渤健马萨诸塞州股份有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115501218-A | Methods of treating multiple sclerosis | 渤健马萨诸塞州股份有限公司 | 2022-12-23 | — | — | CN | disclosed |