SCHEMBL30129786

SCHEMBL30129786

[2H]C([2H])([2H])c1ccc(-c2ccc([Si](C)(C)C)cn2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.39
CCR5 P51681 1/20 0.39
CCR8 P51685 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
KDM1A O60341 1/20 0.38
CYP3A4 P08684 1/20 0.36
CYP2A6 P11509 1/20 0.36
AURKA O14965 1/20 0.34
ABL1 P00519 1/20 0.34
NTRK1 P04629 1/20 0.34
LCK P06239 1/20 0.34
CSF1R P07333 1/20 0.34
RET P07949 1/20 0.34
MET P08581 1/20 0.34
PDGFRB P09619 1/20 0.34
PIM1 P11309 1/20 0.34
PDGFRA P16234 1/20 0.34
FLT3 P36888 1/20 0.34
MAPK8 P45983 1/20 0.34
CDK8 P49336 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32663655 0.91 CCR1 (0.42) CCR1CCR5CCR8HDAC6KDM1A
SCHEMBL23645511 0.82 CCR1 (0.52) CCR1CCR5CCR8HDAC6KDM1A
SCHEMBL29918678 0.82 CCR1 (0.52) CCR1CCR5CCR8HDAC6KDM1A
SCHEMBL1093102 0.81 CCR1 (0.58) CCR1CCR5CCR8HDAC6KDM1A
SCHEMBL29505097 0.79 LDHA (0.48) CYP3A4CHRNA7HPGDSLDHA
SCHEMBL17780846 0.79 LDHA (0.48) CYP3A4CHRNA7HPGDSLDHA
SCHEMBL195553 0.77 CCR1 (0.48) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL17702706 0.74 CCR1 (0.30) CCR1CCR5CCR8HDAC6
Bromide SCHEMBL197909 0.73 CCR1 (0.44) CCR1CCR5CCR8HDAC6METAP2
SCHEMBL15695148 0.73 CYP3A4 (0.50) CCR1CCR5CCR8HDAC6CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115466616-A Composition, layer including the composition, light emitting device including the composition, and electronic device including the light emitting device 三星电子株式会社 2022-12-13 CN disclosed