Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3007173 | 0.86 | MAPT (0.46) | MAPTATMSMN1; SMN2THRBELANE | |
| SCHEMBL335076 | 0.85 | SMN1; SMN2 (0.50) | MAPTATMSMN1; SMN2THRBPOLB | |
| SCHEMBL333931 | 0.84 | MAPT (0.45) | MAPTATMSMN1; SMN2THRBELANE | |
| SCHEMBL3016031 | 0.84 | MAPT (0.45) | MAPTATMSMN1; SMN2THRBELANE | |
| SCHEMBL3571150 | 0.84 | MAPT (0.45) | MAPTATMSMN1; SMN2THRBELANE | |
| SCHEMBL3009481 | 0.83 | KMT2A (0.50) | MAPTATMSMN1; SMN2THRBPOLB | |
| SCHEMBL4698938 | 0.83 | MAPT (0.42) | MAPTATMSMN1; SMN2THRBELANE | |
| SCHEMBL333693 | 0.83 | MAPT (0.43) | MAPTATMSMN1; SMN2THRBELANE | |
| SCHEMBL3012396 | 0.83 | MAPT (0.43) | MAPTATMSMN1; SMN2THRBELANE | |
| SCHEMBL3011590 | 0.82 | MAPT (0.43) | MAPTATMSMN1; SMN2THRBELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197687-A1 | Indoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197687-A1 | Indoles Useful in the Treatment of Inflammation | IDO1, IDO2, TPH1 | MAPT 68/4885ATM 2080/4885SMN1; SMN2 3984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.