Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30075951 | 0.92 | LMNA (0.44) | LMNASMN1; SMN2POLBGBA2ALDH1A1 | |
| SCHEMBL30075791 | 0.91 | LMNA (0.49) | LMNASMN1; SMN2POLBGBA2ALDH1A1 | |
| SCHEMBL30129889 | 0.82 | LMNA (0.47) | LMNASMN1; SMN2POLBGBA2ALDH1A1 | |
| SCHEMBL30075982 | 0.81 | LMNA (0.46) | LMNASMN1; SMN2POLBGBA2ALDH1A1 | |
| SCHEMBL4968757 | 0.80 | LMNA (0.53) | LMNASMN1; SMN2POLBGBA2ALDH1A1 | |
| SCHEMBL4968751 | 0.80 | LMNA (0.53) | LMNASMN1; SMN2POLBGBA2ALDH1A1 | |
| SCHEMBL30129908 | 0.78 | LMNA (0.51) | LMNASMN1; SMN2POLBGBA2ALDH1A1 | |
| SCHEMBL30129902 | 0.78 | LMNA (0.51) | LMNASMN1; SMN2POLBGBA2ALDH1A1 | |
| SCHEMBL23768087 | 0.78 | NR1H2 (0.50) | SMN1; SMN2ALDH1A1HPGDNR1H2PDE4D | |
| SCHEMBL29655416 | 0.77 | LMNA (0.50) | LMNASMN1; SMN2POLBGBA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4103549-A1 | PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS | Syngenta Crop Protection AG (CH) | 2022-12-21 | — | — | EP | disclosed |