Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 14/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | DTYMK | P23919 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31119383 | 1.00 | ENPP2 (0.49) | ENPP2DDB1CRBNHDAC1HDAC6 | |
| SCHEMBL30130278 | 0.92 | DDB1 (0.50) | ENPP2DDB1CRBNHDAC1HDAC6 | |
| SCHEMBL30130173 | 0.92 | ENPP2 (0.49) | ENPP2DDB1CRBNHDAC1HDAC6 | |
| SCHEMBL31119382 | 0.92 | ENPP2 (0.49) | ENPP2DDB1CRBNHDAC1HDAC6 | |
| SCHEMBL31119373 | 0.91 | ENPP2 (0.60) | ENPP2DDB1CRBN | |
| SCHEMBL31119370 | 0.91 | ENPP2 (0.49) | ENPP2DDB1CRBNHDAC1HDAC6 | |
| SCHEMBL30130209 | 0.91 | ENPP2 (0.49) | ENPP2DDB1CRBNHDAC1HDAC6 | |
| SCHEMBL31119379 | 0.91 | ENPP2 (0.49) | ENPP2DDB1CRBNHDAC1HDAC6 | |
| SCHEMBL30130166 | 0.91 | ENPP2 (0.60) | ENPP2DDB1CRBN | |
| SCHEMBL30130281 | 0.91 | ENPP2 (0.49) | ENPP2DDB1CRBNHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611896-A | Compound containing tetralone or tetrahydropyridopyrimidone skeleton and preparation method and pharmaceutical application thereof | 中国药科大学 | 2023-01-17 | — | — | CN | disclosed |