Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24711071 | 1.00 | TSHR (0.41) | TSHRGRM5ALDH1A1LMNATP53 | |
| SCHEMBL19693650 | 0.86 | MEN1 (0.46) | GRM5MEN1KMT2AKCNH2CYP1A2 | |
| SCHEMBL30130720 | 0.86 | MEN1 (0.43) | TSHRALDH1A1LMNATP53ALOX15 | |
| SCHEMBL24711385 | 0.86 | MEN1 (0.43) | TSHRALDH1A1LMNATP53ALOX15 | |
| SCHEMBL30130735 | 0.84 | TSHR (0.40) | TSHRALDH1A1LMNATP53ALOX15 | |
| SCHEMBL30121339 | 0.80 | MEN1 (0.44) | MEN1KMT2AKCNH2 | |
| SCHEMBL19693503 | 0.75 | KMT2A (0.51) | GPBAR1MEN1KMT2AKCNH2 | |
| SCHEMBL25006784 | 0.75 | PSMB5 (0.35) | GPBAR1MEN1KMT2ACYP1A2 | |
| SCHEMBL24981612 | 0.75 | MEN1 (0.39) | GRM5GPBAR1MEN1KMT2AKCNH2 | |
| SCHEMBL29946706 | 0.75 | MEN1 (0.39) | GRM5GPBAR1MEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022257047-A1 | DIAZASPIROBICYLIC COMPOUNDS AS PROTEIN-PROTEIN INTERACTION INHIBITORS AND APPLICATIONS THEREOF | ACERAND THERAPEUTICS (HONG KONG) LIMITED (CN) | 2022-12-15 | — | — | WO | disclosed |