Butyric Acid

Butyric Acid

SCHEMBL3013187

CCC(O)C(=O)O.CCCC(=O)O

nearest known ligand 0.62

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.62
HDAC3 O15379 1/20 0.62
HDAC1 Q13547 1/20 0.62
HDAC2 Q92769 1/20 0.62
HDAC8 Q9BY41 1/20 0.62
TET2 Q6N021 3/20 0.52
KDM4A O75164 2/20 0.52
KDM4C Q9H3R0 2/20 0.52
KDM2A Q9Y2K7 2/20 0.52
TET3 O43151 1/20 0.52
GPR84 Q9NQS5 4/20 0.45
FFAR1 O14842 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
AKR1B1 P15121 1/20 0.42
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.41
SLC22A8 Q8TCC7 1/20 0.41
PPARG P37231 1/20 0.41
PPARD Q03181 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyric Acid SCHEMBL28218040 0.98 FFAR3 (0.59) FFAR3HDAC3HDAC1HDAC2HDAC8
Valeric Acid SCHEMBL29915 0.86 AKR1B1 (0.56) GPR84FFAR1AKR1B1ALDH1A1TSHR
Butane SCHEMBL28113316 0.85 GPR84 (0.52) HDAC1HDAC2GPR84FFAR1SMN1; SMN2
Hexanoate SCHEMBL585328 0.85 AKR1B1 (0.67) GPR84FFAR1AKR1B1ALDH1A1TSHR
SCHEMBL264859 0.84
SCHEMBL15717118 0.84 OR51E2 (0.53) TET2KDM4AKDM4CKDM2ATET3
SCHEMBL6963 0.84
SCHEMBL15355768 0.84
SCHEMBL193026 0.84
Butyric Acid SCHEMBL6532700 0.84 TET2 (0.62) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1274564-B1 ENGINEERED CRACK-RESISTANT PAPER AND BOARD INT PAPER CO (US) 2010-12-01 EP claimed
US-7749596-B1 Engineered crack-resistant paper and board INTERNATIONAL PAPER COMPANY (US) 2010-07-06 US claimed
EP-1274564-A4 ENGINEERED CRACK-RESISTANT PAPER AND BOARD INT PAPER CO (US) 2006-12-06 EP claimed
EP-1274564-A1 ENGINEERED CRACK-RESISTANT PAPER AND BOARD International Paper Company (US) 2003-01-15 EP claimed
WO-2001066344-A1 ENGINEERED CRACK-RESISTANT PAPER AND BOARD INTERNATIONAL PAPER COMPANY (US) 2001-09-13 WO claimed
EP-1274564-B1 ENGINEERED CRACK-RESISTANT PAPER AND BOARD INT PAPER CO (US) 2010-12-01 EP disclosed