Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25885038 | 1.00 | EGFR (0.36) | EGFRXDHLMNATP53HPGD | |
| SCHEMBL30275015 | 0.90 | EGFR (0.35) | EGFRXDH | |
| SCHEMBL25885043 | 0.82 | EGFR (0.37) | EGFRXDHPDE4B | |
| SCHEMBL30132046 | 0.82 | EGFR (0.37) | EGFRXDHPDE4B | |
| SCHEMBL30131949 | 0.78 | PTGDR2 (0.37) | EGFRLMNATP53HPGDHTT | |
| SCHEMBL21412269 | 0.78 | PTGDR2 (0.37) | EGFRLMNATP53HPGDHTT | |
| SCHEMBL25313346 | 0.71 | HTT (0.51) | HTT | |
| SCHEMBL30132015 | 0.71 | HTT (0.51) | HTT | |
| SCHEMBL21412032 | 0.69 | PDE4B (0.32) | EGFRPDE4B | |
| SCHEMBL21412104 | 0.69 | FGFR1 (0.39) | EGFRPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768762-A | Compounds for the treatment of huntington's disease | PTC医疗公司 | 2023-03-07 | — | — | CN | disclosed |
| EP-4132923-A1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC Therapeutics, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |