Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25885043 | 1.00 | EGFR (0.37) | EGFRXDHFYNPDE4B | |
| SCHEMBL30132040 | 0.82 | EGFR (0.36) | EGFRXDHPDE4B | |
| SCHEMBL25885038 | 0.82 | EGFR (0.36) | EGFRXDHPDE4B | |
| SCHEMBL30275015 | 0.79 | EGFR (0.35) | EGFRXDH | |
| SCHEMBL21412242 | 0.78 | MAPK1 (0.35) | EGFR | |
| SCHEMBL30131990 | 0.78 | MAPK1 (0.35) | EGFR | |
| SCHEMBL25313346 | 0.72 | HTT (0.51) | — | |
| SCHEMBL30132015 | 0.72 | HTT (0.51) | — | |
| SCHEMBL30132080 | 0.71 | DGAT1 (0.36) | — | |
| SCHEMBL21412239 | 0.71 | DGAT1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4132923-A1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC Therapeutics, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |